Pancreatin is a pancreatic enzyme combination. It works by providing extra digestive enzymes, which improves digestion, also improve digestion of fatty foods. Pancreatin contains amylase, lipase, and protease – chemicals that help to digest food. These chemicals are normally produced by the pancreas and that are needed for proper digestion. Pancreatin is used as medicine to treat digestion problems that result when the pancreas is not working well. Pancreatin is also used for intestinal gas (flatulence) and as a digestive aid.